Effects of ketogenic diet on muscle function and muscle recovery from injury

2012 Fiscal Year Final Research Report

• Project/Area Number: 24650334
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: St. Marianna University School of Medicine
• Principal Investigator: KAKEHASHI Chiaki 聖マリアンナ医科大学, 医学部, 研究技術員 (80535683)
• Project Period (FY): 2012
• Keywords: リハビリテーション医学

Research Abstract

The propose of this study was to clarify the effect of ketogenic diet on the muscle recovery after muscular injury. Muscle injury was induced by cardiotoxin induction on rat hindlimb muscle and the muscle recovery was evaluated two and four weeks later. However, we could not found any improvement of muscle recovery compared to control diet animals, although there is no halmful influence. On the other hand, ketogenic diet inhibited the increase in body weight compared to control diet. This suggests that ketogenic diet could play a role in control of body weight without muscle functional decline.