2013 Fiscal Year Final Research Report
Studies on function and usage of anhydroglucitol
| Project/Area Number |
24650480
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Osaka City University |
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Principal Investigator |
KONISHI Yotaro 大阪市立大学, 大学院生活科学研究科, 教授 (70116812)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 1,5-アンヒドログルシトール / 甘味料 / オンジ / 1,5-アンヒドロフルクトース |
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| Research Abstract |
We purified 1,5-anhydroglucitol (AG) from Polygala tenuifolia root and characterized its function and utilization from the viewpoint of food science. Such approach has not so far been done. We obtained the following results. (1) AG had 58% of the sweetness of sucrose by sensory evaluation. (2) When AG was orally given to rats (375 mg/kg body weight), about 55% of dose was excreted into urine within 9 hours, suggesting that AG is metabolically stable. Blood AG level returned the basal level 3 days later. (3) It is well known that 1,5-anhydrofructose (AF) is a multi-functional sugar with anti-oxidant, anti- bacterial, anti-obesity, anti-tumor activities, etc. We observed the optimum conditions to produce AF from AG using pyranose oxidase, with a conversion rate of 88%. AF showed anti-browning activity.
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