2014 Fiscal Year Final Research Report
Effects of functional nutrients on the transcription, synthesis and metabolism of apolipoprotein B-48.
| Project/Area Number |
24650503
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Jissen Women's University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | apolipoprotein B48 / intestine / cell culture / transcription / APOBEC1 / curcumin / genistein / resveratrol |
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| Outline of Final Research Achievements |
In order to elucidate the effects of food ingredients on chylomicron metabolism, which leads to postprandial hyperlipidemia a potent risk factor of cardiovascular diseases, we ivetigated the secretion of chylomicron triglyceride and apoB48, for which we have developed monoclonal ELISA, from human intestinal cell Caco-2.
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| Free Research Field |
脂質代謝学、動脈硬化学
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