2013 Fiscal Year Final Research Report
cryoimmunotherapy for malignant bone tumors
| Project/Area Number |
24650631
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Tumor immunology
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 凍結免疫 |
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| Research Abstract |
The purpose of this study is that the cryotreatment of tumor tissue may induced anti tumor effect, and that suppressed tumor recurrence and metastases. We have treated 25 patients for malignant tumors who failed standard treatment of surgery, chemotherapy, and radiotherapy. Then we started dendritic cell immunotherapy generated extra vivo, which pulsed with cryotreated tumor tissue mixed with OK-432. 3o% of patients induced immunological reactions. After that, we planed that the patients treated by cry treatment using liquid nitrogen combined with dendritic cell immunotherapy to reduce local recurrence and metastasis.
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