2013 Fiscal Year Final Research Report
Development of aggregation control protein crystallization apparatus
| Project/Area Number |
24651164
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
MIYATAKE Hideyuki 独立行政法人理化学研究所, 連携支援ユニット, 専任研究員 (50291935)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | タンパク質結晶 / タンパク質結晶化装置 / ナノ会合制御 |
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| Research Abstract |
We developed a solution circulating crystallization apparatus, which can grow protein crystals in the rational way. We can control the nano-aggregation of the protein molecules by changing the solution composition in the apparatus, which optimizes the chance of crystallization. We observed the sample protein crystallization with the apparatus.
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