2013 Fiscal Year Final Research Report
DNA amplification conserving DNA methylation patterns
| Project/Area Number |
24651214
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Genome biology
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| Research Institution | Osaka University |
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Principal Investigator |
TAJIMA Shoji 大阪大学, たんぱく質研究所, 教授 (50132931)
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| Co-Investigator(Kenkyū-buntansha) |
KIMURA Hironobu 大阪大学, 蛋白質研究所, 助教 (60378891)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 生物工学 / DNAメチル化 / DNAメチル化酵素 |
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| Research Abstract |
We have succeeded in establishing the method to distinguish methylated and hydroxymethylated cytosine in a single nucleotide resolution using recombinant maintenance DNA methyltansferase Dnmt1, which favors to methylate hemi-methylated DNA.
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Research Products
(18 results)
