2013 Fiscal Year Final Research Report
The study on the mechanism of sodium ion transport by sodium ion pump rhodopsin
| Project/Area Number |
24655009
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical chemistry
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| Research Institution | Nagoya Institute of Technology |
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Principal Investigator |
INOUE Keiichi 名古屋工業大学, 工学(系)研究科(研究院), 助教 (90467001)
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| Co-Investigator(Renkei-kenkyūsha) |
KANDORI Hideki 名古屋工業大学, 大学院工学研究科, 教授 (70202033)
KOGURE Kazuhiro 東京大学, 大気海洋研究所, 教授 (10161895)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | ロドプシン / ナトリウムポンプ / 赤外分光 / 過渡吸収 / レチナール |
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| Research Abstract |
In this study, we investigated the sodium ion (Na+) transport mechanism by Na+-pumping rhodopsin (NaR) found from marine bacteria in our recent research. For that purpose, especially, we focused the view point of "function", "dynamics" and "structure". As the result, we revealed that NaR pumps Li+ and H+ in addition to Na+ in according to the environment, the reaction process relating to the transport activity, and the place of Na+ binding site. The results relating this study were reported in eight papers and fourty-two presentation in conferences, and three newspaper reports were conducted.
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[Journal Article] A blue-shifted light-driven proton pump for neural silencing2013
Author(s)
Yuki Sudo, Ayako Okazaki, Hikaru Ono, Jin Yagasaki, Seiya Sugo, Motoshi Kamiya, Louisa Reissig, Keiichi Inoue, Kunio Ihara, Hideki Kandori, Shin Takagi and Shigehiko Hayashi
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Journal Title
The Journal of Biological Chemistry
Volume: 288, issue 28
Pages: 20624-20632
DOI
Peer Reviewed
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[Presentation]2013
Author(s)
加藤善隆、井上圭一、大野光、吉住玲、神取秀樹
Organizer
日本生体エネルギー研究会、第39回討論会
Place of Presentation
静岡
Year and Date
2013-12-19
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[Presentation] ロドプシンの謎に分子科学は迫れるか?
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[Remarks] 受賞1.井上圭一 平成26年度文部科学大臣表彰・若手研究者賞、研究テーマ「微生物型ロドプシンの物理化学研究」
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[Remarks] 井上圭一 平成25年度公益財団法人光科学技術研究振興財団 研究表彰、研究テーマ「光駆動型ナトリウムポンプの発見」
