2013 Fiscal Year Final Research Report

Development of compact fluorescence polarization measurement devices

Research Project

Project/Area Number	24655054
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Single-year Grants
Research Field	Analytical chemistry
Research Institution	Hokkaido University
Principal Investigator	TOKESHI Manabu 北海道大学, 工学(系)研究科(研究院), 教授 (60311437)
Project Period (FY)	2012-04-01 – 2014-03-31
Keywords	生体分析
Research Abstract	Compact fluorescence polarization measurement systems for analyzing the interaction between biomolecules and between biomolecule-drug was developed. In this study, we developed a compact fluorescence polarization detection device using fiber optics and a lotion prism and a system using a liquid crystal display and a CCD detector, and evaluated these performances. From these evaluation, both were able to confirm that fluorescence polarization measurement was possible. The device and system developed here can be miniaturized easily, and these achievements lead to the realization of a cheap compact apparatus for fluorescence polarization measurement.

(4 results)