2013 Fiscal Year Final Research Report
Development of compact fluorescence polarization measurement devices
| Project/Area Number |
24655054
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
TOKESHI Manabu 北海道大学, 工学(系)研究科(研究院), 教授 (60311437)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 生体分析 |
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| Research Abstract |
Compact fluorescence polarization measurement systems for analyzing the interaction between biomolecules and between biomolecule-drug was developed. In this study, we developed a compact fluorescence polarization detection device using fiber optics and a lotion prism and a system using a liquid crystal display and a CCD detector, and evaluated these performances. From these evaluation, both were able to confirm that fluorescence polarization measurement was possible. The device and system developed here can be miniaturized easily, and these achievements lead to the realization of a cheap compact apparatus for fluorescence polarization measurement.
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