Development of ion source which forms non-dissociated negative ions with high sensitivity

2014 Fiscal Year Final Research Report

• Project/Area Number: 24655067
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Analytical chemistry
• Research Institution: Osaka Prefecture University
• Principal Investigator: HAYAKAWA Shigeo 大阪府立大学, 理学(系)研究科(研究院), 教授 (00156423)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 質量分析法 / 負イオン生成 / 表面電離 / アルカリ金属 / 電子移動 / 生体分子 / タンデム質量分析法

Outline of Final Research Achievements

Nobel Prize in Chemistry in 2012 indicates that the development of the ionization method in the mass spectrometry is very important. Under the investigation for high-energy electron transfer dissociation using alkali metal targets, we has accidentally found a phenomenon that intense negative ions are formed from a surface which is covered by alkali metal. New ionization method using this phenomenon was developed.
Negative ion spectra were measured for perfluorokerosene (CnF2n+2). While negative ions whose m/z are lower than 1000u were major ions observed by negative chemical ionization method, intense negative ions whose m/z are higher than 1000 u were observed by the newly developed ion source. From this comparison, it is demonstrated that the newly developed ion source using electron transfer from alkali metal on the surface is very soft ionization method for chemical whose mass are higher than 1000 u.

Free Research Field

分析化学