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2014 Fiscal Year Final Research Report

Development of novel molecular recognition surface based on dendrimers

Research Project

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Project/Area Number 24655069
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Analytical chemistry
Research InstitutionSophia University

Principal Investigator

HAYASHITA Takashi  上智大学, 理工学部, 教授 (70183564)

Co-Investigator(Kenkyū-buntansha) ENDO Akira  上智大学, 理工学部, 准教授 (00119124)
HASHIMOTO Takeshi  上智大学, 理工学部, 助教 (20333049)
Project Period (FY) 2012-04-01 – 2015-03-31
Keywords分子認識 / フェニルボロン酸 / ジピコリルアミン錯体 / 糖認識 / アニオン認識 / 細菌認識 / デンドリマー / 機能界面
Outline of Final Research Achievements

For realizing highly selective ion and molecule recognition by artificial sensors, it is quite important to design a multipoint recognition site possessing spacial regulation such as lectin in the biological systems. In this study, selective recognition of sugars, metal ions, phosphate derivatives, and vacteria have been successfully performed by constructing the spacially regulated multipoint recognition sites of boronic acid probes and dipicolylamine probes on the surface of dendrimers known as the woody type polymer.

Free Research Field

分析化学

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Published: 2016-06-03  

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