2013 Fiscal Year Final Research Report
nanomanipulationof antibody based on liquid-binding peptide
| Project/Area Number |
24656496
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Tohoku University |
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Principal Investigator |
UMETSU Mitsuo 東北大学, 工学(系)研究科(研究院), 准教授 (70333846)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | ナノバイオ / 分子認識 / 蛋白質 |
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| Research Abstract |
Recently, we identified the peptide with affinity for liquid surface. In this study, we tried to use the peptide for manipulating proteins on liquid surface and clustering peptide in water solution. Consequently, the fusion of the liquid-binding peptide to GFP resulting in the formation of GFP membrane on the water-ionic liquid interface and the fusion of the peptide to antibody fragment led to the clustering of antibody fragment with avidity effect.
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[Journal Article] Rapid and sensitive detection of brain-derived neurotrophic factor (BDNF) with a plasmonic chip2013
Author(s)
Keiko Tawa, Mari Satoh, Koichi Uegaki, Tomoko Hara, Masami Kojima, Hiroyuki Aota, Yoshiki Yokota, Takahiko Nakaoki, Mitsuo Umetsu, Hikaru Nakazawa, and Izumi Kumagai
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Journal Title
Japanese Journal of Applied Physics
Volume: 52
Pages: 6GK01
DOI
Peer Reviewed
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[Journal Article] Quantum Dot Motion on Microtubules2012
Author(s)
Aurélien Sikora, Daniel Oliveira, Kyongwan Kim, Andrew L. Liao, Mitsuo Umetsu, Izumi Kumagai, Tadafumi Adschiri, Wonmuk Hwang, and Winfried Teizer
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Journal Title
Chemistry Letters
Volume: 41
Pages: 1215-1217
DOI
Peer Reviewed
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