2013 Fiscal Year Final Research Report
Construction of a cell-analyzing biochip
| Project/Area Number |
24656500
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
MIHARA Hisakazu 東京工業大学, 生命理工学研究科, 教授 (30183966)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | バイオチップ / ペプチド / 細胞 |
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| Research Abstract |
To approach the goal of high-throughput analysis of cancer cells, the study on development of biochips using peptide ligands with various cell interaction abilities was performed. A peptide library showing various cell-penetration activities was successfully constructed. The different activities were converted to the color-bar codes regarded as cell finger print patterns. The mechanism of peptide cell-penetration was also examined.
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