2013 Fiscal Year Final Research Report
Body on a Chip: in vitro living model using human pluripotent stem cells
| Project/Area Number |
24656502
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Kyoto University |
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Principal Investigator |
KAMEI Kenichiro 京都大学, 物質ー細胞統合システム拠点, 助教 (00588262)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | マイクロ流体デバイス / ヒト多能性幹細胞 / 組織工学 |
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| Research Abstract |
In this research, we will develop "Body on a Chip" by accomplishing three aims, 1) development of microfluidic platform for construction of 3D micro tissues, 2) construction of 3D micro tissues using human pluripotent stem cells (hPSCs) and 3) development of "Body on a Chip" by interconnecting multiple 3D micro tissue within a microfluidic device.
Specifically, A. Development of high throughput microfluidic device (HT-microFD); B. Establishment of multiple 3D micro tissues within a HT-microFD using hPSCs; C. Construction of of "Body on a Chip" by interconnecting multiple 3D micro tissue within a microfluidic device.
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