2013 Fiscal Year Final Research Report
Regulation of alternative splicing in response to heat-stress
| Project/Area Number |
24657118
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Molecular biology
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| Research Institution | Kobe University |
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Principal Investigator |
INOUE Kunio 神戸大学, 理学(系)研究科(研究院), 教授 (40252415)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 遺伝子 / 発現制御 / 細胞環境 / スプライシング |
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| Research Abstract |
It is known that RNA splicing is repressed in response to heat-stress. Here we examined if the U1 snRNP-independent splicing plays a role in efficient splicing of hsp genes under heat condition. Moreover, we identified an RNA-binding protein required for induction of alternative splicing of hsp105 in response to heat-stress.
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