2014 Fiscal Year Final Research Report
morphological diversity and robustness in phylotypic stage
Project/Area Number |
24657164
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Evolutionary biology
|
Research Institution | Keio University |
Principal Investigator |
HOTTA Kohji 慶應義塾大学, 理工学部, 講師 (80407147)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Keywords | ascidian / ciona / phylotypic / morphogenesis / scaling / giant / chordate / evolution |
Outline of Final Research Achievements |
Ascidian can produce normal-looking miniature tailbud embryos (dwarf embryo) even if unfertilized egg was partially removed. By using this dwarf embryo, we investigated how egg volume influenced on the afterward development at single cell level. As a result, it was found that several tissues (notochord, muscle and endoderm) kept the number of cells in dwarf embryo. On the other hand, other tissues (epidermis, neuron cells and mesenchyme) kept the size of each cell. However, the volume ratio of each tissue in whole-volume was same among dwarf and WT embryo. It was suggested that there is a robust mechanism to maintain a constant ratio of tissue volume regardless of egg volume.
|
Free Research Field |
進化発生生物学
|