2013 Fiscal Year Final Research Report
Analysis and application of lipid metabolisms in anaerobic bacteria for reducing trans fatty acid in foods derived from ruminant animals
| Project/Area Number |
24658079
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | Kyoto University |
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Principal Investigator |
OGAWA Jun 京都大学, (連合)農学研究科(研究院), 教授 (70281102)
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| Co-Investigator(Kenkyū-buntansha) |
ANDO Akinori 京都大学, 生理化学研究ユニット, 助教 (10537765)
KISHINO Shigenobu 京都大学, 大学院農学研究科, 助教 (40432348)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | トランス脂肪酸 / 嫌気性微生物 / 飽和化 / 反芻動物 / FAD / NADH / オレイン酸 / 乳酸菌 |
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| Research Abstract |
Trans fatty acids in foods are reported to have bad effects on health. Trans fatty acids are found in foods derived from ruminant animals such as cow and sheep. Low trans fatty acid is recommended for health. In this research, it was found that hydratase catalyzing the first step of the polyunsaturated fatty acid saturation metabolism is involved in trans fatty acid generating systems. The ratio of cis/trans fatty acid was influenced by the activity control of the hydratase.
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Research Products
(12 results)
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[Journal Article] Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition2013
Author(s)
Kishino, S., M. Takeuchi, S.B Park, A. Hirata, N. Kitamura, J. Kunisawa, H. Kiyono, R. Iwamoto, Y.Isobe, M. Arita, H. Arai, K. Ueda, J. Shima, S. Takahashi, K. Yokozeki, S. Shimizu, J. Ogawa
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Journal Title
Proc. Natl. Acad. Sci. USA
Volume: 110 (44)
Pages: 17808-17813
DOI
Peer Reviewed
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