2013 Fiscal Year Final Research Report

Study on surface-recognition signaling which induce surface adhesion in filamentous fungi

Research Project

Project/Area Number	24658087
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Single-year Grants
Research Field	Applied microbiology
Research Institution	National Institute of Agrobiological Sciences
Principal Investigator	NISHIMURA Marie 独立行政法人農業生物資源研究所, 植物科学領域植物・微生物間相互作用研究ユニット, 主任研究員 (30370670)
Project Period (FY)	2012-04-01 – 2014-03-31
Keywords	バイオフィルム / 糸状菌 / シグナル伝達
Research Abstract	Controlling of fungal biofilms has been an important issue to supply clean environments for industrial, medical and living purposes. Biofilm formation in Ascomycete filamentous fungi starts with the fungal adhering to substrate surfaces. This surface adhesion apperes to be induced by fungal recognition of the surface physiological cues. In this project, we studied mechanisms that triggered adhesion in the Ascomycete fungi, Magnaporthe oryzae. Our results suggested that recognition signaling of certain surface cues negatively regulated the fungal adhesion. We also identified a conserved cell wall protein which was involved in the surface adhesion. Our study will contribute to the further understanding of fungal adhesion mechanisms and the development of anti-biofilm technologies.

(3 results)