2012 Fiscal Year Final Research Report
Development of chiral cyanine dyes containing distorted π-planes
| Project/Area Number |
24659001
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2012
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| Keywords | 合成化学 / キラル / 生体分子 / 薬学 / 有機化学 / シアニン / インジゴ |
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| Research Abstract |
Described here is the development of chiral cyanine dyes and Indigo (Russig's Blue) dyes. The molecular design is based on the use of distorted chiral polycyclic aromatic compounds, by which the aromatic part of known achiral aromatic dyes is substituted. Symmetric (M,M)-cyanine was synthesized from (M)-helicenedicarboxylate. The resulted green compound was characterized by spectroscopic methods, and exhibited notable solvatochromism. Chiral Indigo (Russig Blue) was also synthesized from chiral naphthalene.
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