2014 Fiscal Year Final Research Report
Development of new reaction by controlling the electric and steric natures of phosphine atom
| Project/Area Number |
24659005
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | In situ protection / エノン / ケトン / ホスホリルトリメチルシリルエノールエーテル |
|---|
| Outline of Final Research Achievements |
In situ protection methodology for chemoselective one-pot transformation of ketones, reduction and nucleophilic alkylation, has been achieved in the presence of enones. Discrimination of enones depend on the substituent pattern at their beta-positions has also attained.
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| Free Research Field |
精密合成化学
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