2012 Fiscal Year Final Research Report
Establishment of Breakthrough on Unactivated Alkane C-H Bond Amination
| Project/Area Number |
24659006
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | The University of Tokushima |
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Principal Investigator |
OCHIAI Masahito 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (50127065)
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| Project Period (FY) |
2012
|
| Keywords | 有機化学 |
|---|
| Research Abstract |
Our project involves a development of new research field “chemistry of hypervalent bromane”. We have developed a new methodology for direct regioselective alkane C-H amination, which involves in situ generation of iminobromane. Iminobromane generated from diacyloxybromane by the reaction with triflylamide in alkane as a solvent undergoes alkane C-H amination. Excellent regioselectivity as well as stereoselectivity were observed in the reaction.
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Research Products
(10 results)
