2013 Fiscal Year Final Research Report
Novel strategies to identify the antiviral compounds against highly pathogenic viruses
| Project/Area Number |
24659209
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Virology
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| Research Institution | Nagasaki University |
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Principal Investigator |
YASUDA Jiro 長崎大学, 熱帯医学研究所, 教授 (10282518)
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| Co-Investigator(Renkei-kenkyūsha) |
KUROSAKI Yohei 長崎大学, 熱帯医学研究所, 助教 (40415443)
URATA Shuzo 長崎大学, 熱帯医学研究所, 助教 (20614449)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 診断・治療 / 創薬 |
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| Research Abstract |
By in silico screening using super computer DEGIMA system, we selected 374 chemical compounds as antiviral candidates which inhibit ebolavirus assembly. Antiviral activities of these compounds are currently under investigation.
We also established the high-through put screening system to identify the chemical compounds which inhibit Lassa virus assembly.
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