2014 Fiscal Year Final Research Report
Identification of retrovirus-like DNA fragments in an AIDS patient
| Project/Area Number |
24659212
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Virology
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
KATANO Harutaka 国立感染症研究所, その他部局等, その他 (70321867)
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| Co-Investigator(Renkei-kenkyūsha) |
KURODA Makoto 国立感染症研究所, 病原体ゲノム解析研究センター, センター長 (80317411)
HASEGAWA Hideki 国立感染症研究所, 感染病理部, 部長 (30301790)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | ウイルス |
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| Outline of Final Research Achievements |
Genome fragments of unidentified retrovirus were discovered from the spleen tissue of an AIDS autopsy using a next generation sequencer. The whole genome of the retrovirus was 8kb of length containing gag, pol, env and protease genes, and belonged to beta-retrovirus family. A real-time PCR assay revealed that any genome of the virus was not detected in other human pathological samples, suggesting that the virus is rare and uncommon among human.
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| Free Research Field |
感染病理学
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