2012 Fiscal Year Final Research Report
Analysis of unknown pathogen using human hepatocyte chimeric mouseand massive parallel sequencing
| Project/Area Number |
24659368
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Gastroenterology
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| Research Institution | Hiroshima University |
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Principal Investigator |
CHAYAMA Kazuaki 広島大学, 大学院・医歯薬保健学研究院, 教授 (00211376)
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| Project Period (FY) |
2012
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| Keywords | ウイルス、ゲノム / 細胞・組織 / 肝細胞キメラマウス |
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| Research Abstract |
We attempted to identify unknown pathogen from a patient with eruption and liver disorder with massive parallel sequencing. We found DNA sequences of cytomegalovirus from this patient. Further assembly of remaining non-human sequence is now going on.
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[Journal Article] Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders2012
Author(s)
Chayama K, Takahashi S, Toyota J, Karino Y, Ikeda K, Ishikawa H, et al
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Journal Title
Hepatology
Volume: 55
Pages: 742-748
DOI
Peer Reviewed
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