2013 Fiscal Year Final Research Report
Improvement of Social Cognition Employing Real-time fMRI-based Neuro-feedback
| Project/Area Number |
24659546
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Tamagawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OKUBO Yoshiro 日本医科大学, 医学研究科, 教授 (20213663)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 精神科リハビリテーション |
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| Research Abstract |
Neuro-feedback refers to the method whereby a subject monitors his/her own neural activity in a particular brain region of interest, and gains the ability to willfully control the level of neural activity. Recently, self-monitoring of neural activity in subcortical and other deep brain areas, as well as areas related to higher-order brain function, became possible with the development of real-time fMRI. The purpose of this research is to develop the task of improvement of social cognition employing real-time fMRI-based neuro-feedback.
It is evident that pervasive developmental disorders (PDD) subjects are able to increase amygdala activity through neuro-feedback training, and that in order to willfully control amygdala activity, simultaneous activity in the insula and MPFC are necessary. Moreover, after the neuro-feedback training, the neural sensitivity of amygdala is increased.
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