2013 Fiscal Year Final Research Report
Study of the differentiation of respiratory epithelium using iPS cells
| Project/Area Number |
24659751
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
OMORI KOICHI 福島県立医科大学, 医学部, 教授 (10233272)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKAMURA Tatsuo 京都大学, 再生医科学研究所, 准教授 (70227908)
WADA Ikuo 福島県立医科大学, 医学部, 教授 (40182969)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | iPS細胞 / 再生医学 / 気管上皮 |
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| Research Abstract |
The purpose of this study is to establish a technique to differentiate mouse induced pluripotent stem (iPS) cells to respiratory epithelial tissue and to regenerate tracheal tissue. The presence of respiratory epithelium-like tissue was observed after several days culture by hematoxylin eosin staining and immunohistochemistry. This is the first study to demonstrate the potential of iPS cells for regeneration of the respiratory epithelium.
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