Development of the new skin grafting method (micro cube skin grafting) which has a high wound healing effect.

2015 Fiscal Year Final Research Report

• Project/Area Number: 24659778
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Plastic surgery
• Research Institution: Hirosaki University
• Principal Investigator: Urushidate Satoshi 弘前大学, 医学(系)研究科(研究院), 教授 (80321967)
• Co-Investigator(Kenkyū-buntansha): YOKOI Katsunori 弘前大学, 大学院医学研究科, 講師 (00271809) ; MIKAMI Makoto 弘前大学, 大学院医学研究科, 助教 (30396402)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 組織移植 / 創傷治癒 / 熱傷 / 皮膚移植 / 皮膚潰瘍

Outline of Final Research Achievements

The micro cube skin grafting is a new skin grafting method that minced small cube skins are grafted on the skin ulcer. The utility of this method was investigated using skin ulcers of rats, and we have revealed whether this method had the better wound healing effects compared to the traditional methods. The grafted skins using this method were well survived under the moist environment in spite of the direction of the skin.　The epithelialization was observed not only from the edge of the epithelium but also from the cutaneous appendixes. After four weeks, the epithelialized area from the grafted skin spread to 28~113 times of the original size. In conclusion, it was considered that the micro cube skin grafting is a useful method for the treatment of severe burns.

Free Research Field

形成外科学