Development of In vivo tissue engineered autologous tube grafts "Biotubes" for suturess microvascular reconstruction

2014 Fiscal Year Final Research Report

• Project/Area Number: 24659786
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Plastic surgery
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: WATANABE Taiji 京都府立医科大学, 医学(系)研究科(研究院), 助教 (20448723)
• Co-Investigator(Kenkyū-buntansha): OHBA Kenkichi 関西大学, 付属研究所, 研究員 (30029186) ; NAKAYAMA Yasuhide 独立行政法人国立循環器病研究センター, 生体医工学部, 室長 (50250262) ; KANDA Keiichi 京都府立医科大学, 医学(系)研究科(研究院), 講師 (60295649) ; TAJIKAWA Tsutomu 関西大学, 工学部, 准教授 (80351500)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: biotube / 生体内組織形成技術 / 小口径代用血管

Outline of Final Research Achievements

In this study,　we aim to develop the sutureless biotube as application of the complete autologous connective tissue small diameter vascular graft" biotube" which are constructed by "in body tissue architecture" technology under the novel concept of the D.I.Y. regenerative medicine. By using this sutureless biotube, we can reconstruct any small caliber vessels such as artery, vein, lymphatics without anastomosing. In this study period, we succeeded to integrate biotubes and native vesssels without anastomosing.

Free Research Field

血管外科