2013 Fiscal Year Final Research Report
The identification of maintenance mechanism of mesenchymal stem cells based on the niche concept of SCAP.
| Project/Area Number |
24659875
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KUBOKI Takuo 岡山大学, 医歯薬学総合研究科, 教授 (00225195)
ONO Mitsuaki 岡山大学, 医歯薬学総合研究科, 助教 (60613156)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 幹細胞性維持機構 / ニッチ / SCAP |
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| Research Abstract |
It is well known that adult tissue stem cells, which exit in the niche, are involved in the maintenance or restoration of homeostasis in various tissue. In this research, we focused Ccn4 gene and that revealed that Ccn4 gene could be involved in tooth development and wound healing. In future, we will clarify the relationship between Ccn4 gene and maintenance mechanism of niche.
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