2013 Fiscal Year Final Research Report
Energy metabolism and muscle pathology in swallowing muscles after electric nerve stimulation
| Project/Area Number |
24659882
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
INOUE Nobuo 北海道大学, 大学院歯学研究科, 特任教授 (20091415)
YAMAZAKI Yutaka 北海道大学, 大学院歯学研究科, 教授 (90250464)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 筋線維タイプ / 咀嚼筋 / ATPase |
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| Research Abstract |
Swallowing mechanism are very complicated and muscle pathology of the swallowing muscles has yet to be clarified. Histochemical characteristics of the human masticatory muscles and swallowing muscles were investigated in this study. Experimental studies of soft diet using young rabbits were also performed. Human masseter muscle and swallowing muscle showed unique histochemical characterstics reflecting highly differentiated masticatory and swallowing function. The soft diet experiment showed transformation of the muscle fiber types, suggesting that long-term soft diet leads to adaptations of the pterygoid
muscles. Two heads of the lateral pterygoid muscle revealed different adaptation from jaw-closing muscles
under soft-diet conditions.
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