Development of the drug nanocrystal eye drops for treatment retinal diseases

2014 Fiscal Year Final Research Report

• Project/Area Number: 24680054
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Osaka University
• Principal Investigator: BABA Koichi 大阪大学, 医学(系)研究科(研究院), 寄附講座准教授 (00436172)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: ナノバイオ材料 / 点眼液 / 薬剤ナノ結晶

Outline of Final Research Achievements

Eye drop treatment is one of the effective manner to cure ocular disease. However, because of the several barrier functions of eye, comparably low amount of the drug can penetrate into ocular globe. In this time, we succeeded in preparing drug nanocrystal eye drops using freeze-drying technology. The drug nanocrystal eye drops showed enhanced ocular penetration rate of eye drops. We want to extend this technique to cure retinal diseases in near future.

Free Research Field

有機ナノ材料化学