2014 Fiscal Year Final Research Report
Cell society formation during vertebrate organogenesis
| Project/Area Number |
24681043
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
System genome science
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| Research Institution | Nara Institute of Science and Technology |
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Principal Investigator |
MATSUI Takaaki 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (60403333)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 発生・分化 |
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| Outline of Final Research Achievements |
During vertebrate organogenesis, cells are autonomously gathered and make a functional cell cluster called a cell society. However, even though cells are put together in vitro, cells are not able to generate the cell society. How cell society is generated during organogenesis remains largely unknown. We have used zebrafish organogenesis (for instance, formation of endoderm-derived organs, Kupffer’s vesicles and somites) as a model for cell society formation, and found several factors which are necessary for generating the cell society during organogenesis.
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| Free Research Field |
発生生物学
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