Synthesis of biomolecular clusters on the scaffolds of hollow spherical complexes

2014 Fiscal Year Final Research Report

• Project/Area Number: 24685010
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Inorganic chemistry
• Research Institution: Tohoku University (2013-2014); The University of Tokyo (2012)
• Principal Investigator: SATO Sota 東北大学, 原子分子材料科学高等研究機構, 准教授 (40401129)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 自己組織化 / 生体分子インターフェース / 球状錯体

Outline of Final Research Achievements

Well-defined biomolecular clusters were synthesized by the decoration of biomolecules on the inside/outside periphery of several nanometer-sized spherical complexes, and the unique recognition properties of the biomolecular clusters were revealed. The well-defined, dense biomolecular clusters were self-assembled, whose detailed structures were clearly determined. Interface recognition with one of the world's biggest molecular scale was achieved for the target substrates of inorganic materials or biomolecules. The weak recognition ability of each biomolecular substituent was enhanced by the accumulation effect on the spherical complexes, and the distinct structure-function relationship at a molecular level was confirmed on the newly developed molecular systems.

Free Research Field

有機化学