Cross talk between RNA silencing and plant innate immune responses to viruses

2015 Fiscal Year Final Research Report

• Project/Area Number: 24688005
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Plant pathology
• Research Institution: The University of Tokyo
• Principal Investigator: YAMAJI YASUYUKI 東京大学, 農学生命科学研究科, 准教授 (40345187)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 植物・病原体相互作用

Outline of Final Research Achievements

Plants combat with viruses using two defense mechanisms, RNA silencing and plant innate immunity. In this study, we analyzed the role of an RNA silencing suppressor, TGBp1. We found that TGBp1 interacted with Arabidopsis thaliana proteins SGS3 and RDR6, both of which are involved in double-stranded RNA synthesis, to aggregate and inactivate their activities in planta. We also analyzed the mechanism of JAX1-mediated resistance and revealed the a viral protein responsible for it. Based on these results, we elucidated various plant-virus molecular interactions.

Free Research Field

農学