2013 Fiscal Year Final Research Report
Mechanism of auditory cortex to store and recall the pattern of sounds analyzed by two photon imaging
Project/Area Number |
24700320
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Neuroscience in general
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Research Institution | Niigata University |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Keywords | 大脳聴覚野 / 和音 / マウス / 脳機能イメージング / マウス / 記憶 / 連想 |
Research Abstract |
Harmony is a kind of sounds whose components' frequencies are in relation of an integer ratio. Animals perceive the fundamental frequency (F0) which is the greatest common factor of harmonic sounds even if it does not exist. We observed mouse primary auditory cortex with two photon imaging and flavoprotein fluorescence imaging to investigate the neural mechanism to generate this phenomenon. As a result, it was revealed that the primary auditory cortex works as an associative memory circuit, and F0 is one of the components recalled by an associative memory circuit.
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