2013 Fiscal Year Final Research Report
Research of neural network basis for generating spatiotemporal activity patterns of animal locomotion
| Project/Area Number |
24700395
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KOHSAKA Hiroshi 東京大学, 新領域創成科学研究科, 助教 (20431900)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | ニューロン / シナプス / 神経回路 / 遺伝学 |
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| Research Abstract |
Each animal moves in a certain speed. Though this observation seems obvious, it is still almost unclear how neural circuits generate speed of animal locomotion. In this study, using a motor circuit of Drosophila larvae as a model system, which is amenable to detailed analyses of neuronal networks, we examined the mechanisms of speed control of the larval locomotion. We found that a subset of interneurons, we named per-IN, regulate speed of locomotion by shortening the duration of motor neuronal activities.
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