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2013 Fiscal Year Final Research Report

Functional significance of parasagittal clusters formed by cerebellar Purkinje cells

Research Project

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Project/Area Number 24700401
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Neurophysiology and muscle physiology
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

YAMADA Yoshiyuki  独立行政法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 (80553685)

Project Period (FY) 2012 – 2013
Keywords小脳 / 神経回路 / in vivo / 2光子イメージング / Ca^<2+>イメージング
Research Abstract

Parasagettal clusters formed by cerebellar Purkinje cells were visualized by fluorescent protein introduced by adenovirus vector, the activity of which were monitored by in vivo Ca^<2+> imaging. Spontaneous activity and sensory responses of Purkinje cells were successfully recorded with a single-cellular resolution and in reference to the parasagittal clusters.

  • Research Products

    (2 results)

All 2013 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] Improved detection of electrical activity with a voltage probe based on a voltage-sensing phosphatase2013

    • Author(s)
      Tsutsui, H., Jinno, Y., Tomita, A., Niino, Y., Yamada, Y., Mikoshiba, K., Miyawaki A., and Okamura Y.
    • Journal Title

      J. Physiol.

      Volume: 591 Pages: 4427-37

    • Peer Reviewed
  • [Journal Article] Quantitative comparison of novel GCaMP-type genetically encoded Ca^<2+> indicators in mammalian neurons2012

    • Author(s)
      Yamada, Y. and Mikoshiba, K.
    • Journal Title

      Q Front. Cell. Neurosci.

      Volume: 6 Pages: 41

    • DOI

      doi: 10.3389/fncel.2012.00041

    • Peer Reviewed

URL: 

Published: 2015-03-12  

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