2013 Fiscal Year Final Research Report
Basic and clinical study on inhibitory modulation of motor function using a regulatory focal brain cooling
| Project/Area Number |
24700420
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Fusional brain recording science
|
|---|
| Research Institution | Yamaguchi University |
|---|
Principal Investigator |
IMOTO HIROCHIKA 山口大学, 医学部附属病院, 診療助教 (80464337)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | 脳機能計測 / 局所脳冷却 / 脳機能マッピング |
|---|
| Research Abstract |
The neurosurgical treatment for diseases such as intractable epilepsy and brain tumors, functional localization of the brain is evaluated by functional brain mapping. However, There is a problem such as accidentally induced convulsion by electrical stimulation. In this study, we investigated the effects on brain function by focal brain cooling.
As a result, the boundary of the cooling temperature to cause dysfunction, was 10-15 degC. Further, if the cooling at 15 degC does not cause loss of function, brain function was not disrupted. Therefore, the focal brain cooling is reversible brain function control method could be confirmed.
|
-
[Journal Article] Changes in glutamate concentration, glucose metabolism, and cerebral blood flow during focal brain cooling of the epileptogenic cortex in humans2014
Author(s)
Sadahiro Nonura, Masami Fujii, Takao Inoue, Yeting He, Yuichi Maruta, Hiroyasu Koizumi, Eiichi Suehiro, Hirochika Imoto, Hideyuki Ishihara, Fumiaki Oka, Mishiya Matsumoto, Yuji Owada, Takeshi Yamakawa, and Michiyasu Suzuki
-
Journal Title
Epilepsia
Volume: Vol.55(5)
Pages: 770-776
DOI
Peer Reviewed
-
-
-
-
-
