2014 Fiscal Year Final Research Report
Analysis of visual functions by neurophysiological methods for evaluation of stress responses
| Project/Area Number |
24700451
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 瞳孔反応 / 自律神経系 / ストレス反応 / サーカディアンリズム / 視覚機能 |
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| Outline of Final Research Achievements |
Autonomic nervous system, which controls pupillary behaviors, might be damaged by stressors. We developed the monitoring methods of the nervous system and the circadian rhythms of several autonomic functions by using pupillary analyses. We used blue (470nm) and red (640nm) light stimuli for inducing of pupillary light responses. The blue light especially stimulates the melanopsin-expressing retinal ganglion cells (mRGCs), which contributes to the coordination of circadian rhythms. The pupillary response to the blue stimulation well correlated with heart rate variations and the response to the red light showed fine correlation with body temperature changes. These pupillary behaviors could be a maker for biological rhythms regulated by autonomic nervous system.
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| Free Research Field |
神経生理学，生体医工学
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