2014 Fiscal Year Final Research Report
Does long-term exercise reduce the nitration of organs caused by inflammation in rat infection model?
| Project/Area Number |
24700704
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Sports science
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| Research Institution | Hokuriku University (2013-2014)
Juntendo University (2012) |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | タンパク質ニトロ化 |
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| Outline of Final Research Achievements |
Aim of the research is to know contribution of long-term spontaneous movements for the prevention of organ damage caused by the infection. In this research, it was able to obtain the knowledge in infection model animals and exercise model animals. In the infection model with lipopolysaccharide administration, the fate of the intensity and time variation of the response of nitrating and oxidative stress markers with the dose of lipopolysaccharide are different for each organ. The mice that do not have a moderate exercise, highly expression level of Mn- superoxide dismutase and large amount of oxygen consumption per body weight were observed.
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| Free Research Field |
環境健康学
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