2013 Fiscal Year Final Research Report
Study of the responsible compounds for contact dermatitis caused by the formaldehyde releasers in cosmetics
| Project/Area Number |
24700796
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General human life sciences
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| Research Institution | Osaka Prefectural Institute of Public Health |
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Principal Investigator |
TAKAHIRO Doi 大阪府立公衆衛生研究所, 衛生化学部, 主任研究員 (90516767)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 化粧品 / 防腐剤 / 皮膚感作性 / ジアゾリジニル尿素 / イミダゾリジニル尿素 / DMDMヒダントイン |
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| Research Abstract |
We have developed the method to determine formaldehyde-releasers in cosmetics. Using the developed method, we identified unknown compounds derived from formaldehyde-releasers in cosmetics. Two common decomposition products were found from cosmetics containing imidazolidinyl urea and diazolidinylurea. These common decomposition compounds were possible causative agent of cross-reaction between imidazolidinyl urea and diazolidinyl urea.
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