2014 Fiscal Year Final Research Report
Development effect of a fermented product of soybean milk by indigenous lactic acid bacteria on lipid metabolism
| Project/Area Number |
24700854
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Nagasaki International University |
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Principal Investigator |
NODAKE Yuichi 長崎国際大学, 薬学部, 講師 (30332282)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 乳酸菌生産物質 / 脂質代謝 / 機能性食品 |
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| Outline of Final Research Achievements |
PS-B1 is a fermented product cultivated from soybean milk using indigenous lactic acid bacteria. In this study, we obtained results showing that PS-B1 improved lipid metabolism by inhibiting lipid metabolism-related genes in mouse 3T3-L1 cells and rat hepatocytes. DNA microarray analysis suggested that PS-B1 controls the expression of 39 genes and has an effect on 69 metabolic pathways in hepatocytes in C57BL/6J mice, with 14 of these 69 pathways being strongly influenced by PS-B1.
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| Free Research Field |
生化学
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