2013 Fiscal Year Final Research Report
Construction of rigid polymer conjugated oligonucleotide
| Project/Area Number |
24710125
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Suzuka University of Medical Science |
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Principal Investigator |
TASHIRO Ryu 鈴鹿医療科学大学, 薬学部, 助教 (00402785)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | ＤＮＡデバイス |
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| Research Abstract |
DNA is a powerful tool for creating nanosized architectures and devices owing to its synthetic accessibility and ability to self-assemble. We designed and synthesized a novel H-shaped DNA oligonucleotide dimer cross-linked with a rigid linker. The formation of these motifs was observed via native polyacryla-mide gel analysis and a fluorescence resonance energy transfer experiment using labeled DNA.
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[Journal Article]2014
Author(s)
Sannohe, Y.; Kizaki, S.; Kanesato, S.; Fujiwara, A.; Morinaga, H.; Tashiro, R.; Sugiyama, H.
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Journal Title
Chem. Eur. J
Volume: 20
Pages: 1223-1225
DOI
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[Journal Article]2013
Author(s)
Morinaga, H.; Kizaki, S.; Takenaka, T.; Kanesato, S.; Sannohe, Y.; Tashiro, R.; Sugiyama, H.
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Journal Title
Bioorg. Med. Chem
Volume: 21
Pages: 466-469
DOI
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