Modeling of cell tissue morphology: Cell adhesion force and cellular arrangement

2014 Fiscal Year Final Research Report

• Project/Area Number: 24740292
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Biophysics/Chemical physics
• Research Institution: Tokyo University of Agriculture and Technology (2014); Kyushu University (2012-2013)
• Principal Investigator: YANAGISAWA Miho 東京農工大学, 工学(系)研究科(研究院), 特任准教授 (50555802)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 細胞モデル / 界面張力 / 細胞接着

Outline of Final Research Achievements

Living cells regulate their shapes and cytoplasmic structures to be appropriate for their functions. To reveal the mechanism to regulate their shapes and structures, we used adhering droplets entrapping a polymer blend as a model of cellular tissue, and investigated relation between adhesion force between the cells and cellular arrangement. Consequently, it is found that the adhesive force and the cellular arrangement have a codependent relationship via structural formation of the polymer blend in cells.

Free Research Field

ソフトマター物理