2013 Fiscal Year Final Research Report
Mechanistic Studies of Synthetic Organic Reactions Using Quantitative Mass Spectrometry
| Project/Area Number |
24750036
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | University of Shizuoka |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 有機合成化学 / 質量分析 / 反応機構 / 触媒 / 反応中間体 |
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| Research Abstract |
In this study, mechanistic study using mass spectrometry was conducted by detecting trace amounts of unstable catalysts and reaction intermediates. Use of soft ionization method enabled detection of such species. In the same time, reaction monitoring by combining mass spectrometer and autosampler was tried to realize quantification of chemical species in the reaction.
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