Colorimetric sensing of amino acids based on a surface-enhanced photochromic phenomena (SEPP) of tungsten(VI) oxide nanoparticles.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24750069
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Analytical chemistry
• Research Institution: Yamaguchi University
• Principal Investigator: ADACHI KENTA 山口大学, 理工学研究科, 准教授 (80535245)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 分析化学 / アミノ酸 / センシング / ナノ粒子 / フォトクロミズム / ポリオキソメタレート / 吸着

Outline of Final Research Achievements

We have demonstrated, for the first time, the use of surface-enhanced photochromic phenomena for sensitive label-free α-amino acid (α-AA) sensing using the WO3 colloid nanoparticles as a colorimetric probe. A good linear correlation between the initial coloration rate and the surface concentration of α-AA on the WO3 can be obtained over 3 orders of magnitude, and a low detection limit for α-AA of ca. 9.0×10-12 mol dm-2 (1.0×10-6 M at pH 2) can be achieved.

Free Research Field

分析化学