2013 Fiscal Year Final Research Report
Fabrication of photonic crystal for high-sensitive label-free biosensor
| Project/Area Number |
24750073
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Analytical chemistry
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
ENDO Tatsuro 大阪府立大学, 工学(系)研究科(研究院), 准教授 (40432017)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | バイオセンサー / フォトニック結晶 / ナノインプリントリソグラフィー |
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| Research Abstract |
For the future medical application, high-sensitive and simplified biosensor for detection of target molecules based on antigen-antibody reaction has been strongly desired. In this study, for development of novel high-sensitive biosensor, polymer-based photonic crystal (PhC) which has a periodic nanostructure was fabricated. For biosensor application, polymer-PhCs with different design (size, periodicity, and structure) were fabricated using electron beam lithography, and the sensing performances (sensitivity and dynamic range) using antibody-antigen reaction were investigated.
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