2013 Fiscal Year Final Research Report
Study for synthesis of organic molecules based on chiral organometallic catalysts containing C,N-polydentate ligands
| Project/Area Number |
24750084
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Nagoya University |
|---|
Principal Investigator |
ITO Jun-ichi 名古屋大学, 工学(系)研究科(研究院), 講師 (20402480)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | 不斉金属触媒 / 多座配位子 / ピンサー型錯体 / オキサゾリン配位子 / カルベン配位子 |
|---|
| Research Abstract |
In this study, we elucidated the development of new transition metal catalyst containing carbon-nitrogen based chiral polydentate ligands. As a result, we have successfully synthesized new polydentate ligands containing oxazoline and N-heterocyclic carbene fragments and their transition metal complexes having rhodium, iridium, cobalt and ruthenium. In those catalysts, we developed several types of asymmetric transformations, namely asymmetric conjugate reduction of a,b-unsaturated carbonyl compounds, direct asymmetric alkynylation of aldehydes. In addition, we also found that pincer type iridium complexes exhibited C-H activation reaction of benzene derivatives and they served as a catalyst on bolylation reaction of aromatic compounds. Furthermore, the iridium complex was successfully applied to C-H activation of unactivated alkanes, giving the corresponding alkyl complexes.
|
Research Products
(15 results)
