2013 Fiscal Year Final Research Report

Syntheses of Novel Transition Metal-Carbene Complexes Effective for C-H Bond Activation of Alkanes and Development of New Synthetic Reactions

Research Project

Project/Area Number	24750086
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Synthetic chemistry
Research Institution	Kyoto University
Principal Investigator	YADA Akira 京都大学, 工学(系)研究科(研究院), 助教 (70619965)
Project Period (FY)	2012-04-01 – 2014-03-31
Keywords	有機金属化学 / 炭素―水素結合 / 不活性結合活性化
Research Abstract	New rhodium complexes that are ligated by N-heteroaromatic carbenes were synthesized, and, under photo irradiation condition, their catalytic activities toward carbon-hydrogen bond activations of arenes and alkanes were investigated. However, the rhodium complexes were less reactive for the reactions. When the carbonylation reaction was carried out in the presence of carbonyl compounds, the acceleration effect was observed. During the course of the research directed toward the syntheses of more active transition metal complexes, palladium-catalyzed dehydrogenative coupling reaction of terminal alkynes with alkenes, and rhodium-catalyzed enantioselective synthesis of cyclopentanols from cyclobutanols were achieved.

(5 results)