2013 Fiscal Year Final Research Report
Non-equilibrium statistical mechanics for fluctuations in cells
| Project/Area Number |
24770143
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biophysics
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| Research Institution | Tohoku University |
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Principal Investigator |
HAYASHI Kumiko 東北大学, 工学(系)研究科(研究院), 助教 (00585979)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 1分子計測・操作 |
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| Research Abstract |
We measured the motion of mitochondria in PC12 cells by using fluorescent observation. A mitochondrion is transported by motor proteins such as kinesin and dynein along microtubules. We investigated the fluctuation-dissipation theorem for this non-equilibrium phenomenon. Comparing motion of Brownian beads incorporated into the cells by electroporation method, we experimentally found that the fluctuation-dissipation theorem was not valid for the motion of a mitochondrion.
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