2013 Fiscal Year Final Research Report
Characterization of the environmental signal transduction system in bacterial cell-cell communication and cell aggregation
| Project/Area Number |
24780070
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Applied microbiology
|
|---|
| Research Institution | Shinshu University |
|---|
Principal Investigator |
OGASAWARA Hiroshi 信州大学, ヒト環境科学研究支援センター, 助教 (30535232)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | Biofilm / csgD / curli / Escherichia coli / Transcription / signal transduction |
|---|
| Research Abstract |
In the natural environments, the many bacterial species exposed to much complicated stress forms biofilm and raises resistance for physical and chemical factors received from such external environment. In this study, we performed the systematic analysis to clarify expression control of CsgD protein playing a central role of the biofilm formation of Escherichia coli, and searched for received signals and the regulatory factors for the csgD expression and clarified some new mechanism. We hope to promote this study to understand the molecular switching mechanism of response to environmental change of the bacterial genome expression pattern in the biofilm formation.
|
-
[Journal Article] Screening of promoter-specific transcription factors : multiple regulators for the sdiA gene involved in cell division control and quorum sensing2013
Author(s)
Shimada, K., Ogasawara, H., Yamada, K., Shimura, M., Kori, A., Shimada, T., Yamanaka, Y., Yamamoto, K., Ishihama, A.
-
Journal Title
Microbiology
Volume: 159
Pages: 2501-2512
Peer Reviewed
-
[Journal Article] Identification of the set of genes, including non-annotated morA, under the direct control of ModE in Escherichia coli2013
Author(s)
Kurata, T., Katayama, A., Hiramatsu, M., Kiguchi, Y., Takeuch, M., Watanabe, T., Ogasawara, H., Ishihama, A., Yamamoto, K.
-
Journal Title
Bacteriol
Volume: 195
Pages: 4496-4505
Peer Reviewed
-
[Journal Article] A novel regulator RcdA of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli2012
Author(s)
Shimada, T., Katayama, Y., Kawakita, S., Ogasawara, H., Nakano, M., Yamamoto, K., Ishihama, A.
-
Journal Title
Microbiologyopen
Volume: 1
Pages: 381-394
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
